2015年3月9日 訊近日，在聖地牙哥舉辦的第97屆美國內分泌學會會議上，來自德爾塔州立大學的研究人員通過研究表示，洋蔥萃取物可以明顯降低患糖尿病大鼠的血壓並及總膽固醇水準。
研究者Anthony Ojieh說道，洋蔥非常便宜而且容易獲得，其通常用作營養補充劑，而其對治療糖尿病卻有潛在的用途；洋蔥萃取物可以明顯快速降低糖尿病大鼠的血糖水準，而研究發現在降膽固醇上會帶來極大的效應。
最後研究者Ojieh說道，我們需要更為深入的研究來解釋洋蔥降低血糖的分子機制，希望能找到洋蔥對康糖尿病的有效成分做為新藥用途。
"Onion is cheap and available and has been used as a nutritional supplement," said lead investigator Anthony Ojieh, MBBS (MD), MSc, of Delta State University in Abraka, Nigeria. "It has the potential for use in treating patients with diabetes."
To three groups of rats with medically induced diabetes, Ojieh and his colleagues gave metformin and varying doses of onion extract--200, 400 and 600 milligrams per kilograms of body weight daily (mg/kg/day)--to see if it would enhance the drug's effects. They also gave metformin and onion extract to three groups of nondiabetic rats with normal blood sugar, for comparison. Two control groups, one nondiabetic and one diabetic, received neither metformin nor onion extract. Another two groups (one with diabetes, one without) received only metformin and no onion extract. Each group contained five rats.
Two doses of onion extract, 400 and 600 mg/kg/day, strongly reduced fasting blood sugar levels in diabetic rats by 50 percent and 35 percent, respectively, compared with "baseline" levels at the start of the study before the rodents received onion extract, Ojieh reported.
Allium cepa also reportedly lowered the total cholesterol level in diabetic rats, with the two larger doses again having the greatest effects.
Onion extract led to an increase in average weight among nondiabetic rats but not diabetic rats.
"Onion is not high in calories," Ojieh said. "However, it seems to increase the metabolic rate and, with that, to increase the appetite, leading to an increase in feeding."......
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